Dopamine reuptake inhibitor

Dopamine Reuptake Inhibitors or Dopamine Uptake Inhibitors are compounds that inhibit the reuptake of the neurotransmitter

dopamine after it is released and used at the synapse. I

In so doing, DRIs tend to increase the amount of dopamine present in the brain, which increases feelings of enjoyment and motivation.

Other drugs which impact the level of dopamine in the brain include bupropion (Wellbutrin, Zyban), sertraline (Zoloft) (at high doses), Benztropine, Nomifensine, Mazindol, and a new class of reuptake inhibitors, the GBR Series.

Another example of potent dopamine reuptake inhibitor is amineptine which is now banned in most countries including the USA. Amphetamines and cocaine increase the level of dopamine, but are illegal for their hazardous and addictive properties.

Dopamine reuptake inhibitors

• Bupropion (Wellbutrin, Zyban)
• Amineptine (Maneon, Survector)

Antidepressants

Monoamine oxidase inhibitors: Harmaline • Nialamide • Selegiline • Isocarboxazid • Iproniazid • Iproclozide • Moclobemide • Phenelzine • Toloxatone • Tranylcypromine Dopamine reuptake inhibitors: Bupropion • Amineptine Norepinephrine reuptake inhibitors: Atomoxetine • Reboxetine • Viloxazine • Maprotiline Serotonin-norepinephrine reuptake inhibitors: Desipramine • Duloxetine • Milnacipran • Nefazodone • Venlafaxine Selective serotonin reuptake inhibitors: Alaproclate • Etoperidone • Citalopram • Escitalopram • Fluoxetine • Fluvoxamine • Paroxetine • Sertraline • Zimelidine Selective serotonin reuptake enhancers: Tianeptine Tricyclic antidepressants: Amitriptyline • Clomipramine • Desipramine • Dothiepin • Doxepin • Imipramine • Lofepramine • Nortriptyline • Protriptyline • Trimipramine • Iprindole • Opipramol Tetracyclic antidepressants: Maprotiline • Mianserin • Mirtazapine • Amoxapine