Depression Wiki

Dopamine Reuptake Inhibitors or Dopamine Uptake Inhibitors are compounds that inhibit the reuptake of the neurotransmitter

180px-Norepinephrine structure

dopamine after it is released and used at the synapse. I

In so doing, DRIs tend to increase the amount of dopamine present in the brain, which increases feelings of enjoyment and motivation.

Other drugs which impact the level of dopamine in the brain include bupropion (Wellbutrin, Zyban), sertraline (Zoloft) (at high doses), Benztropine, Nomifensine, Mazindol, and a new class of reuptake inhibitors, the GBR Series.

Another example of potent dopamine reuptake inhibitor is amineptine which is now banned in most countries including the USA. Amphetamines and cocaine increase the level of dopamine, but are illegal for their hazardous and addictive properties.

Dopamine reuptake inhibitors[]

Antidepressants edit
Monoamine oxidase inhibitors: {Harmaline} {Nialamide} {Selegiline} {Isocarboxazid} {Iproniazid} {Iproclozide} {Moclobemide} {Phenelzine} {Toloxatone} {Tranylcypromine}

Dopamine reuptake inhibitors: {Bupropion} {Amineptine}

Norepinephrine reuptake inhibitors: {Atomoxetine} {Reboxetine} {Viloxazine} {Maprotiline}

Serotonin-norepinephrine reuptake inhibitors: {Desipramine} {Duloxetine} {Milnacipran} {Nefazodone} {Venlafaxine}

Selective serotonin reuptake inhibitors: {Alaproclate} {Etoperidone} {Citalopram} {Escitalopram} {Fluoxetine} {Fluvoxamine} {Paroxetine} {Sertraline} {Zimelidine}

Selective serotonin reuptake enhancers: {Tianeptine}

Tricyclic antidepressants: {Amitriptyline} {Clomipramine} {Desipramine} {Dothiepin} {Doxepin} {Imipramine} {Lofepramine} {Nortriptyline} {Protriptyline} {Trimipramine} {Iprindole} {Opipramol}

Tetracyclic antidepressants: {Maprotiline} {Mianserin} {Mirtazapine} {Amoxapine}